Performed between 10 weeks, 0 days and 13 weeks, 6 days gestation, the test combines ultrasound markers with the analysis of five biological markers to increase the detection rates and assess risk for:
The chromosome abnormalities screened for in this test including:
- Trisomy 21 (Down syndrome)
- Trisomy 18 (Edwards Syndrome)
- Trisomy 13 (Patau syndrome)
Optional Early Onset Preeclampsia (EOPE)
Early onset preeclampsia is defined as preeclampsia resulting in the delivery of the fetus before 34 weeks’ gestation. It is estimated to occur in approximately 0.5% of all pregnancies. Early onset preeclampsia is less common than the late form of the disorder, but contributes more to the morbidity and mortality of pregnant mothers and babies.
NTD also offers stand -alone preeclampsia screening that does not include a risk assessment for Down syndrome, Trisomy 18 (Edwards Syndrome), or Trisomy 13 (Patau syndrome).
Optional Other Obstetric Complications
By analyzing the biochemical markers in patient’s blood, Maternal Fetal Screen | T1 casts a wide net and also offers insight into other maternal and fetal issues, such as aneuploidy, low birth weight, fetal loss, and stillbirth.
*Information provided if second trimester screening is included
The Advantages of Free Beta hCG:
NTD Eurofins is the only laboratory that utilizes free beta hCG in their prenatal screening protocol. The use of free beta hCG in screening for Down syndrome and other chromosomal abnormalities has been demonstrated to be more effective than intact or total hCG. Intact/total hCG, while an effective second trimester marker, is far less effective during the first trimester.
The American College of Medical Genetics (ACMG) technical guidelines on prenatal screening state the following:
“Before 11 weeks, free beta hCG is discriminatory but hCG is not. Between 11 and 13 gestational weeks, free beta hCG is univariately a more discriminatory Down syndrome screening marker than hCG.”
Uterine Artery Doppler Pulsatility Index
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- Make sure the patient is sitting comfortably with her feet on the floor, legs uncrossed, for about 5 minutes.
- Blood pressure (BP) measured in both arms simultaneously.
- Recordings at 1-minute intervals until stable.
- Enter Left Arm and Right arm BP’s on NTD’s Test Requisition
- MAP is calculated by NTD Labs.
Turn around time: Results can be expected 2-5 days from the time the sample is received at the laboratory.
Early Detection, Early Assurance with Instant Risk Assessment from eReports
First Trimester Screen | Fß with Instant Risk Assessment from eReports enables physicians to present a complete risk assessment for Down syndrome and Trisomy 18 (Edwards Syndrome) and Trisomy 13 (Patau syndrome) during a single office visit and ensure same-day results notification for the patient. As early as 10 weeks gestation, a maternal blood sample can be collected and submitted to NTD. The results of the blood screen are maintained and made available to the physician when the patient undergoes her nuchal ultrasound exam between 11 weeks, 1 day and 13 weeks, 6 days of gestation. To save time, NTD provides web-based access to your patient’s biochemistry data through a secure eReports website.
Learn more about why NTD Eurofins has been the laboratory to trust for over 30 years.Learn More
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